Chemistry:Aminosteroid
From HandWiki
Short description: Class of chemical compounds
Aminosteroids are a group of steroids with a similar structure based on an amino-substituted steroid nucleus.[1][2] They are neuromuscular blocking agents, acting as competitive antagonists of the nicotinic acetylcholine receptor (nAChR), and block the signaling of acetylcholine in the nervous system.[1][2][3] These drugs include candocuronium iodide (chandonium iodide), dacuronium bromide, dihydrochandonium, dipyrandium, malouetine, pancuronium bromide, pipecuronium bromide, rapacuronium bromide, rocuronium bromide, stercuronium iodide, and vecuronium bromide.[2][4]
See also
- Benzylisoquinolines, such as atracurium and tubocurarine, the other major group of neuromuscular blocking agents
References
- ↑ 1.0 1.1 Ted Lin; Tim Smith; Colin Pinnock (1 December 2016). Fundamentals of Anaesthesia. Cambridge University Press. pp. 650–. ISBN 978-1-316-66678-4. https://books.google.com/books?id=o5y0DQAAQBAJ&pg=PA650.
- ↑ 2.0 2.1 2.2 Thomas L. Lemke; David A. Williams (24 January 2012). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 336–337. ISBN 978-1-60913-345-0. https://books.google.com/books?id=Sd6ot9ul-bUC&pg=PA336.
- ↑ Alexandra Dugdale (28 November 2011). Veterinary Anaesthesia: Principles to Practice. John Wiley & Sons. pp. 144–. ISBN 978-1-118-27933-5. https://books.google.com/books?id=0_7MRlsNbnoC&pg=PA144.
- ↑ "Reference at www.who.int". https://www.who.int/medicines/services/inn/StemBook_2013_Final.pdf.
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