Chemistry:Alifedrine

From HandWiki

Alifedrine (INN; developmental code name D-13625) is a drug described as a sympathomimetic and cardiotonic or positive inotropic agent which was never marketed.[1][2][3][4] It is a β-adrenergic receptor partial agonist and was studied in the treatment of heart failure.[2][5][6][7] The drug is taken by mouth or intravenously.[5][6] It is a β-hydroxylated substituted amphetamine derivative.[8]

See also

References

  1. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014. p. 1-PA373. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA28. Retrieved 29 August 2024. 
  2. 2.0 2.1 Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. 1999. p. 10. ISBN 978-0-7514-0499-9. https://books.google.com/books?id=mqaOMOtk61IC&pg=PA10. Retrieved 29 August 2024. 
  3. Pharmaceutical Manufacturing Encyclopedia. Volumes 1-4. Elsevier Science. 2013. p. 155. ISBN 978-0-8155-1856-3. https://books.google.com/books?id=_J2ti4EkYpkC&pg=PA155. Retrieved 2024-08-29. 
  4. "Alifedrine, a positive inotropic agent that moderately reduces the severity of ischaemia and reperfusion-induced ventricular arrhythmias". European Journal of Pharmacology 147 (3): 373–380. March 1988. doi:10.1016/0014-2999(88)90171-9. PMID 3378563. 
  5. 5.0 5.1 "Haemodynamic effects of intravenous and oral alifedrine in patients with cardiac failure". Current Medical Research and Opinion 11 (4): 242–253. 1988. doi:10.1185/03007998809114243. PMID 3215041. 
  6. 6.0 6.1 "Acute haemodynamic effects of different doses of alifedrine in congestive heart failure". European Journal of Clinical Pharmacology 36 (4): 335–341. 1989. doi:10.1007/BF00558291. PMID 2737225. 
  7. "Effects of the novel beta-adrenergic partial agonist alifedrine on cardiac performance in dogs with acute ischemic left ventricular failure". Journal of Cardiovascular Pharmacology 14 (1): 103–108. July 1989. doi:10.1097/00005344-198907000-00018. PMID 2475700. 
  8. "Alifedrine". PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/51719.