Chemistry:Befunolol
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Short description: Chemical compound
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| Trade names | Benfuran, Bentos, Betaclar, Glauconex |
| AHFS/Drugs.com | International Drug Names |
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| Formula | C16H21NO4 |
| Molar mass | 291.347 g·mol−1 |
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Befunolol (INN) is a beta blocker with intrinsic sympathomimetic activity used in the management of open-angle glaucoma.[1] It also acts as a β adrenoreceptor partial agonist.[2][3] Befunolol was introduced in Japan in 1983 by Kakenyaku Kako Co. under the trade name Bentos.[4]
References
- ↑ "The use of a porcine organotypic cornea construct for permeation studies from formulations containing befunolol hydrochloride". International Journal of Pharmaceutics 250 (1): 191–201. January 2003. doi:10.1016/S0378-5173(02)00541-0. PMID 12480285.
- ↑ "A beta-adrenergic partial agonist (befunolol) discriminates two different affinity sites". Japanese Journal of Pharmacology 42 (2): 325–8. October 1986. doi:10.1254/jjp.42.325. PMID 2879061.
- ↑ "A beta-adrenoceptor blocking agent, befunolol as a partial agonist in isolated organs". General Pharmacology 16 (3): 265–7. January 1985. doi:10.1016/0306-3623(85)90080-1. PMID 2862092.
- ↑ Pharmaceutical Manufacturing Encyclopedia (3rd revised ed.). Norwich, N.Y.: William Andrew Publishing. January 14, 2008. p. 542. ISBN 978-0815515265.
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