Chemistry:Indenolol
From HandWiki
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| IUPAC name
1-(1H-Inden-4-yloxy)-3-(propan-2-ylamino)propan-2-ol
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| Properties | |
| C15H21NO2 | |
| Molar mass | 247.338 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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Indenolol is a beta-adrenergic blocker[1] for the treatment of hypertension (high blood pressure). It was investigated in the 1980s,[2] but is not known to be marketed (As of 2021).[3] It is a derivative of a phenolic 4-indenol.
References
- ↑ Ali, I; Gaitonde, VD; Aboul-Enein, HY; Hussain, A (2009). "Chiral separation of beta-adrenergic blockers on CelluCoat column by HPLC". Talanta 78 (2): 458–63. doi:10.1016/j.talanta.2008.11.043. PMID 19203609.
- ↑ Trimarco, Bruno; Cuocolo, Alberto; Groothold, Gisela; Ricciardelli, Bruno; De Luca, Nicola; Volpe, Massimo; Veniero, Anna Maria; Condorelli, Mario (1985). "Indenolol: A New Antihypertensive Agent: Efficacy, Toxicity, and Hemodynamic Effects in a Crossover Double-Blind Study with Metoprolol". The Journal of Clinical Pharmacology 25 (5): 328–336. doi:10.1002/j.1552-4604.1985.tb02850.x. PMID 4031109.
- ↑ DrugBank DB08952 . Accessed 2021-03-18.
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