Chemistry:Amidephrine

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Amidephrine (BAN), or amidefrine, sold under the brand name Fentrinol among others, is a selective α1-adrenergic receptor agonist which is described as an adrenergic or sympathomimetic, vasoconstrictor, and topical nasal decongestant used to treat allergic rhinitis.[1][2][3][4][5] It is used as the mesylate salt, which has the generic names amidefrine mesilate (INN) and amidephrine mesylate (USAN).[2] The drug is a substituted phenethylamine derivative and is also known as 3-methylsulfonamidyl-β-hydroxy-N-methylphenethylamine.[2][1][6] As of 2000, it remained marketed only in Austria.[3]

References

  1. ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014. p. 40. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA40. Retrieved 2024-08-31. 
  2. ↑ 2.0 2.1 2.2 Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Netherlands. 2012. p. 13. ISBN 978-94-011-4439-1. https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA13. Retrieved 2024-08-31. 
  3. ↑ 3.0 3.1 Schweizerischer Apotheker-Verein (2000). Index Nominum 2000: International Drug Directory. Medpharm Scientific Publishers. p. 39. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA39. Retrieved 2024-08-31. 
  4. ↑ "Amidephrine: Uses, Interactions, Mechanism of Action". 24 February 2021. https://go.drugbank.com/drugs/DB16623. 
  5. ↑ "Pressor effects of the alpha 2-adrenoceptor agonist B-HT 933 in anaesthetized and haemorrhagic rats: comparison with the haemodynamic effects of amidephrine". British Journal of Pharmacology 97 (2): 419–432. June 1989. doi:10.1111/j.1476-5381.1989.tb11969.x. PMID 2569342. 
  6. ↑ "Amidephrine". PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/15010. 



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