Chemistry:Phenazolam

From HandWiki
Short description: Chemical compound
Phenazolam
Clobromazolam structure.png
Clinical data
Trade names(none, designer drug)
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H12BrClN4
Molar mass387.7 g·mol−1
3D model (JSmol)

Phenazolam, (Clobromazolam, DM-II-90, BRN 4550445) is a benzodiazepine derivative which acts as a potent sedative and hypnotic drug. It was first invented in the early 1980s,[1] but was never developed for medical use. It has been sold over the internet as a designer drug, first being identified in seized samples by a laboratory in Sweden in March 2016.[2][3]

Legality

Clobromazolam was made illegal in Serbia in May 2019,[4] and in Italy in March 2020.[5]

See also

References

  1. "Potential hypnotics and anxiolytics: 8-Chloro-6-(2-chlorophenyl)-1-[4-(2-methoxyethyl) piperazino]-methyl-4H-s-triazolo[4,3-a]-1,4-benzodiazepine and related compounds.". Collection of Czechoslovak Chemical Communications 48 (12): 3433–43. 1983. doi:10.1135/cccc19833433. 
  2. "Novel Benzodiazepines. A review of the evidence of use and harms of Novel Benzodiazepines.". Advisory Council on the Misuse of Drugs. April 2020. https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/881969/ACMD_report_-_a_review_of_the_evidence_of_use_and_harms_of_novel_benzodiazepines.pdf. 
  3. "Flubromazolam-Derived Designer Benzodiazepines: Toxicokinetics and Analytical Toxicology of Clobromazolam and Bromazolam". Journal of Analytical Toxicology 45 (9): 1014–1027. October 2020. doi:10.1093/jat/bkaa161. PMID 33048135. 
  4. ""Службени гласник РС", број 38 од 31. маја 2019." (in Serbian). Serbian Ministry of Health. http://www.pravno-informacioni-sistem.rs/SlGlasnikPortal/eli/rep/sgrs/ministarstva/pravilnik/2019/38/2/reg. 
  5. "Legislazione - MINISTERO SALUTE - Decreto ministeriale" (in Italian). 13 March 2020. https://www.tcnotiziario.it/Articolo/Index?settings=ZWdiemk3MXMwRlN6QkdoSEVkaElNc1ZqTVVNL2ZQdVRMeFAxOU83ZExEOTF5dk9sVG5tM0E0WEpEbWNHNTIyaTlpSUNvL3RZdHU0bkVEa2cvT2R0eVM2cXBXeTRpWGM1WVlGamIyZ3FSOC9EbVQvTzdTbzNIdXJkRXZVOVRpMVc=.