Chemistry:Metizolam
From HandWiki
Short description: Chemical compound
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| Dependence liability | Moderate |
| Routes of administration | Oral, sublingual, rectal |
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| Formula | C16H13ClN4S |
| Molar mass | 328.82 g·mol−1 |
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Metizolam (also known as desmethyletizolam) is a thienotriazolodiazepine that is the demethylated analogue of the closely related etizolam.[1][2][3][4][5][6]
Legal status
Following its sale as a designer drug,[7] metizolam was classified as controlled substance in Sweden on 26. January 2016.[8]
See also
References
- ↑ "Heteroaromaten mit anellierten Siebenringen, III. Umwandlung von Thienotriazolooxazepinen in Diazepine" (in de). Justus Liebigs Annalen der Chemie 1978 (8): 1257–1265. 20 September 1978. doi:10.1002/jlac.197819780806. ISSN 1099-0690.
- ↑ Nakanishi M, Tahara T, Araki K, Shiroki M, "Triazolothienodiazepine compounds", US patent 3904641, issued 9 September 1975, assigned to Welfide Corp
- ↑ Hiroshi K, Ehara Syuji E, Hideaki S, Moriwaki Minoru M, Kenichi O, "Thienylazole compound and thienotriazolodiazepine compound", EP patent 0776892, published 1997-06-04, assigned to Yoshitomi Pharmaceutical Industries, Ltd.
- ↑ Moriwaki M, Abe M, Mikashima H, Tahara T, "Thieno(triazolo)diazepine compounds and medicinal application of the same", EP patent 0315698, published 1993-03-03, assigned to Yoshitomi Pharmaceutical Industries, Ltd.
- ↑ "Characterization and in vitro phase I microsomal metabolism of designer benzodiazepines - an update comprising adinazolam, cloniprazepam, fonazepam, 3-hydroxyphenazepam, metizolam and nitrazolam". Journal of Mass Spectrometry 51 (11): 1080–1089. November 2016. doi:10.1002/jms.3840. PMID 27535017. Bibcode: 2016JMSp...51.1080M.
- ↑ "Detection of the designer benzodiazepine metizolam in urine and preliminary data on its metabolism". Drug Testing and Analysis 9 (7): 1026–1033. July 2017. doi:10.1002/dta.2099. PMID 27671107.
- ↑ "Desmethyletizolam". New Synthetic Drugs Database. http://nsddb.eu/substance/573/.
- ↑ "31 nya ämnen kan klassas som narkotika eller hälsofarlig vara" (in sv). Folkhälsomyndigheten. November 2015. https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2015/november/31-nya-amnen-kan-klassas-som-narkotika-eller-halsofarlig-vara/.
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