Chemistry:Sulazepam
From HandWiki
Short description: Chemical compound
 | |
| Clinical data | |
|---|---|
| ATC code |
|
| Legal status | |
| Legal status |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| Chemical and physical data | |
| Formula | C16H13ClN2S |
| Molar mass | 300.80 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
| (verify) | |
Sulazepam is a benzodiazepine derivative. It is the thioamide derivative of diazepam. It is metabolised into diazepam, desmethyldiazepam and oxydiazepam[citation needed]. It has sedative, muscle relaxant, hypnotic, anticonvulsant and anxiolytic properties like those of other benzodiazepines.[1][2] It was never marketed.
Synthesis
Treatment of diazepam with phosphorus pentasulfide produces the corresponding thionamide, sulazepam.
See also
References
- ↑ "sulazepam". psychotropics.dk. 2003. http://www.psychotropics.dk/moleculeView/default.aspx?ID=1444&Catalogtype=A&ChapterID=1&Thissortorder=41.
- ↑ "[Analysis of the structure of the components of the convulsive action of corazole following administration of sulazepam and its metabolites to mice]" (in ru). Biulleten' Eksperimental'noi Biologii I Meditsiny 82 (9): 1078–81. September 1976. PMID 11012.
- ↑ "Quinazolines and 1,4-Benzodiazepines. XVI. Synthesis and Transformations of 5-Phenyl-1,4-benzodiazepine-2-thiones". The Journal of Organic Chemistry 29: 231. 1964. doi:10.1021/jo01024a511.
 |  |
