Chemistry:Cloniprazepam
From HandWiki
Short description: Benzodiazepine drug
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| Other names | 1-Cyclopropylmethylclonazepam, Kloniprazepam, 2-Chloro-7'-nitroprazepam |
| Drug class | Benzodiazepines |
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| Formula | C19H16ClN3O3 |
| Molar mass | 369.81 g·mol−1 |
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Cloniprazepam is a benzodiazepine derivative and a prodrug of clonazepam, 7-aminoclonazepam, and other metabolites.[1][2]
Some of the minor metabolites include 3-hydroxyclonazepam and 6-hydroxyclonazepam, 3-hydroxycloniprazepam and ketocloniprazepam with ketone group formed where 3-hydroxy group was.[1]
It is a designer drug and an NPS (short for "new psychoactive substance").[1] At the end of 2017, cloniprazepam was an uncontrolled substance in most of the countries.
See also
- Flutoprazepam
- Ro05-4082
- List of designer drugs
- List of benzodiazepines
- List of benzodiazepine designer drugs
References
- ↑ 1.0 1.1 1.2 "Characterization and in vitro phase I microsomal metabolism of designer benzodiazepines - an update comprising adinazolam, cloniprazepam, fonazepam, 3-hydroxyphenazepam, metizolam and nitrazolam". Journal of Mass Spectrometry 51 (11): 1080–1089. November 2016. doi:10.1002/jms.3840. PMID 27535017. Bibcode: 2016JMSp...51.1080M.
- ↑ "In vitro Phase I and Phase II metabolism of the new designer benzodiazepine cloniprazepam using liquid chromatography coupled to quadrupole time-of-flight mass spectrometry". Journal of Pharmaceutical and Biomedical Analysis 153: 158–167. May 2018. doi:10.1016/j.jpba.2018.02.032. PMID 29494888.
External links
- https://www.unodc.org/LSS/Substance/Details/d115de07-ab8f-4454-a8f7-3ea15f4a0748
- https://web.archive.org/web/20160623204002/http://nsddb.eu/substance/590/
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