Chemistry:Iclazepam

Short description: Chemical compound

Iclazepam

Identifiers
IUPAC name 7-chloro-1-[2-(cyclopropylmethoxy)ethyl]-5-phenyl-3H-1,4-benzodiazepin-2-one
CAS Number	57916-70-8 Y
PubChem CID	68777
ChemSpider	62020 Y
UNII	FL061Q6NMC
ChEMBL	ChEMBL2104257
Chemical and physical data
Formula	C21H21ClN2O2
Molar mass	368.86 g·mol−1
3D model (JSmol)	Interactive image
SMILES ClC1=CC2=C(C=C1)N(CCOCC3CC3)C(CN=C2C4=CC=CC=C4)=O
InChI InChI=1S/C21H21ClN2O2/c22-17-8-9-19-18(12-17)21(16-4-2-1-3-5-16)23-13-20(25)24(19)10-11-26-14-15-6-7-15/h1-5,8-9,12,15H,6-7,10-11,13-14H2 Y Key:PLRHQQPBNXIHAZ-UHFFFAOYSA-N Y
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Iclazepam (Clazepam) is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, and is around the same potency as chlordiazepoxide.

Iclazepam is a derivative of nordazepam substituted with a cyclopropylmethoxyethyl group on the N¹ nitrogen. Once in the body, iclazepam is quickly metabolised to nordazepam and its N-(2-hydroxyethyl) derivative, which are thought to be mainly responsible for its effects.

See also

• List of benzodiazepines