Chemistry:Dimaprit

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Dimaprit
Dimaprit.svg
Names
Preferred IUPAC name
3-(Dimethylamino)propyl carbamimidothioate
Other names
3-dimethylaminopropyl sulfanylmethanimidamide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
KEGG
UNII
Properties
C6H15N3S
Molar mass 161.2684 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Tracking categories (test):

Dimaprit is a histamine analog working as a selective H2 histamine receptor agonist.[1][2][3]

References

  1. Kartzung, Betram G.; Trevor, Anthony J., eds (2014). Basic and Clinical Pharmacology (13th ed.). New York: McGraw-Hill Education. p. 364. ISBN 978-0071825054. 
  2. Kohno, S; Ogawa, K; Nabe, T; Yamamura, H; Ohata, K (May 1993). "Dimaprit, a Histamine H2-agonist, Inhibits Anaphylactic Histamine Release from Mast Cells and the Decreased Release is Restored by Thioperamide (H3-antagonist), but not by Cimetidine (H2-antagonist)". Japanese Journal of Pharmacology 62 (1): 75–9. doi:10.1254/jjp.62.75. PMID 7688057. 
  3. Nakamura, T; Ueno, Y; Goda, Y; Nakamura, A; Shinjo, K; Nagahisa, A (March 1997). "Efficacy of a Selective Histamine H2 Receptor Agonist, Dimaprit, in Experimental Models of Endotoxin Shock and Hepatitis in Mice". European Journal of Pharmacology 322 (1): 83–89. doi:10.1016/S0014-2999(96)00987-9. PMID 9088875.