Chemistry:Histamine trifluoromethyl toluidide

Histamine trifluoromethyl toluidide

Names
IUPAC name 6-[2-(1H-imidazol-5-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]heptanamide
Other names HTFMT, HTMT
Identifiers
CAS Number	103827-16-3 Y
3D model (JSmol)	Interactive image
ChemSpider	111155 N
IUPHAR/BPS	1273
PubChem CID	124846
InChI InChI=1S/C19H25F3N4O/c1-14(24-11-10-17-12-23-13-25-17)4-2-3-5-18(27)26-16-8-6-15(7-9-16)19(20,21)22/h6-9,12-14,24H,2-5,10-11H2,1H3,(H,23,25)(H,26,27) N Key: PMKJGGBYYNEYPA-UHFFFAOYSA-N N InChI=1/C19H25F3N4O/c1-14(24-11-10-17-12-23-13-25-17)4-2-3-5-18(27)26-16-8-6-15(7-9-16)19(20,21)22/h6-9,12-14,24H,2-5,10-11H2,1H3,(H,23,25)(H,26,27) Key: PMKJGGBYYNEYPA-UHFFFAOYAA
SMILES FC(F)(F)c1ccc(cc1)NC(=O)CCCCC(NCCc2cnc[nH]2)C
Properties
Chemical formula	C19H25F3N4O
Molar mass	382.42321
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Tracking categories (test):

• SizeSet

Histamine trifluoromethyl toluidide (HTFMT) is a mixed H₁/H₂ histamine agonist which is significantly more potent than histamine itself.

It also produces additional actions which appear to be independent of histamine receptors.