Chemistry:Mebhydrolin

From HandWiki
Short description: Chemical compound
Mebhydrolin
Mebhydrolin structure.png
Clinical data
Other names9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[1]
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • Not established[2]
Routes of
administration
Oral[2]
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
  • 524-81-2 ☑Y
    6153-33-9 (1,5-naphthalenedisulfonate salt)[3]
PubChem CID
ChemSpider
UNII
KEGG
Chemical and physical data
FormulaC19H20N2[4]
Molar mass276.383 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Mebhydrolin (INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal (BD) and Diazolin (Russia ). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to magnify the performance-deficit effects of alcohol.[5]

References

  1. "Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. https://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=mebhydroline. 
  2. 2.0 2.1 "FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. http://home.intekom.com/pharm/bayer/fabahist.html. 
  3. "Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. https://www.nlm.nih.gov/cgi/mesh/2006/MB_cgi?mode=&term=diazoline. 
  4. "Mebhydrolin chemical information". PubChem. http://www.chemindustry.com/chemicals/969111.html. 
  5. "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9. October 1981. doi:10.5694/j.1326-5377.1981.tb112944.x. PMID 6119605.