Chemistry:OUP-16

From HandWiki
OUP-16
OUP-16.svg
Names
IUPAC name
1-cyano-3-[[(2R,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
Properties
C11H16N6O
Molar mass 248.290 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N (what is ☑Y☒N ?)
Infobox references
Tracking categories (test):

OUP-16 is a histamine agonist selective for the H4 subtype.[1]

References

  1. Hashimoto, T; Harusawa, S; Araki, L; Zuiderveld, OP; Smit, MJ; Imazu, T; Takashima, S; Yamamoto, Y et al. (July 2003). "A Selective Human H4-Receptor Agonist: (−)-2-Cyano-1-methyl-3-{(2R,5R)-5- [1H-imidazol-4(5)-yl]tetrahydrofuran-2-yl}methylguanidine". Journal of Medicinal Chemistry 46 (14): 3162–5. doi:10.1021/jm0300025. PMID 12825954.