Chemistry:VUF-8430
From HandWiki
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| Names | |
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| Preferred IUPAC name
2-[(Aminoiminomethyl)amino]ethyl carbamimidothioic acid ester[citation needed] | |
| Identifiers | |
3D model (JSmol)
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| Abbreviations | VUF-8430 |
| ChEMBL | |
| ChemSpider | |
PubChem CID
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| UNII | |
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| Properties | |
| C4H11N5S | |
| Molar mass | 161.23 g·mol−1 |
| log P | -1.367 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
VUF-8430 is a histamine agonist[1] selective for the H4 subtype.[2]
References
- ↑ "Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury". Neuroimmunomodulation 14 (6): 317–25. 2007. doi:10.1159/000125048. PMID 18401194. https://www.karger.com/Article/PDF/000125048.
- ↑ Lim, HD; Smits, RA; Bakker, RA; Van Dam, CM; De Esch, IJ; Leurs, R (2006). "Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist.". Journal of Medicinal Chemistry 49 (23): 6650–1. doi:10.1021/jm060880d. PMID 17154494.
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