Chemistry:Pimethixene

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Short description: Chemical compound
Pimethixene
Pimethixene.png
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral, nasal
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC19H19NS
Molar mass293.43 g·mol−1
3D model (JSmol)
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Pimethixene is an antihistamine and anticholinergic of the thioxanthene chemical class originally developed to treat hyperactivity,[1] anxiety, sleep disorders, and allergy. It is also used for anesthesia and as a bronchodilator (to dilate the bronchi and bronchioles for more airflow).

In combination with pholcodine, it was sold in France by Laboratoires Salvoxyl in the 1970s as the antitussive Salvodex.[2] Pimethixene alone is still available in Brazil under the trade name Muricalm.

See also

References

  1. "[New treatment of hyperkinesis in the child: pimethixene]". Revue Médicale de Liège 33 (14): 500–3. July 1978. PMID 674966. 
  2. Bailly, Christian (8 December 2020). "Salvodex® (9-(1-methyl, 4-piperylidenyl)thiaxanthene and pholcodine), from Laboratoires Salvoxyl (Orléans), 1971". Oncowitan. https://www.oncowitan.com/2020/12/08/salvodex-9-1-methyl-4-piperylidenylthiaxanthene-and-pholcodine-from-laboratoires-salvoxyl-orleans-1971. Retrieved 4 January 2022.