Chemistry:(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid

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(1,2,5,6-Tetrahydropyridin-4-yl)­methylphosphinic acid
TPMPA structure.svg
Names
Preferred IUPAC name
Methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
Other names
TPMPA
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
Properties
C6H12NO2P
Molar mass 161.141 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid (TPMPA) is a GABA antagonist selective for the GABAA-ρ (previously known as GABAC) subtype.[1]

References

  1. ↑ Li, Shifeng; Zhang, Yunbin; Liu, Haixiong; Yan, Yuanchang; Li, Yiping (2008). "Identification and expression of GABACreceptor in rat testis and spermatozoa". Acta Biochimica et Biophysica Sinica 40 (8): 761–7. doi:10.1111/j.1745-7270.2008.00453.x. PMID 18685793. 

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 | group1 = Ionotropic
 |  list1 = {{Navbox|subgroup
 | groupstyle = text-align:center
 | groupwidth = 5em

   | group1 = GABAA
   | list1  = 

   | group2 = GABAA-ρ
   | list2  = 

 }}

 | group2 = Metabotropic

| list2 =

GABAB
 | below =
See also
Receptor/signaling modulators
GABAA receptor positive modulators
GABA metabolism/transport modulators

}}




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