Chemistry:2,3-Dichlorophenylpiperazine

2,3-Dichlorophenylpiperazine

Names
IUPAC name 1-(2,3-dichlorophenyl)piperazine
Identifiers
CAS Number	41202-77-1 N
3D model (JSmol)	Interactive image
ChemSpider	744460 Y
PubChem CID	851833
InChI InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2 Y Key: UDQMXYJSNNCRAS-UHFFFAOYSA-N Y InChI=1S/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2 Key: UDQMXYJSNNCRAS-UHFFFAOYAH InChI=1/C10H12Cl2N2/c11-8-2-1-3-9(10(8)12)14-6-4-13-5-7-14/h1-3,13H,4-7H2 Key: UDQMXYJSNNCRAS-UHFFFAOYAH
SMILES Clc1c(Cl)c(ccc1)N2CCNCC2
Properties
Chemical formula	C10H12Cl2N2
Molar mass	231.12 g/mol
Appearance	brown oil
Density	1.272g/cm3 °C
Melting point	242 to 244 °C (468 to 471 °F; 515 to 517 K)
Boiling point	365.1 °C (689.2 °F; 638.2 K) at 760mmHg
Hazards
Flash point	174.6 °C (346.3 °F; 447.8 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

2,3-Dichlorophenylpiperazine (2,3-DCPP or DCPP) is a chemical compound. It is both a precursor in the synthesis of aripiprazole and one of its metabolites. It is unclear whether 2,3-DCPP is pharmacologically active similar to its close analogue 3-chlorophenylpiperazine (mCPP).

Legality

2,3-DCPP has been made illegal in Japan and Hungary after having been identified in seized designer drug samples.

Derivatives

As with the related compound mCPP, 2,3-DCPP is an essential precursor to several pharmaceutical drugs which are widely used in medicine, and is also formed as a metabolite of these drugs in patients, although generally only in insignificant amounts.

• Aripiprazole
• Cariprazine

See also

• Substituted piperazine
• Phenylpiperazine