Chemistry:Manidipine
From HandWiki
Short description: Antihypertensive drug of the calcium channel blocker class
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| Trade names | Manyper, Caldine, etc. |
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| Routes of administration | Oral |
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| Formula | C35H38N4O6 |
| Molar mass | 610.711 g·mol−1 |
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Manidipine is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive.[1][2][3][4][5]
It was patented in 1982 and approved for medical use in 1990.[6]
References
- ↑ "Manidipine: a review of its use in hypertension". Drugs 61 (12): 1777–1799. 2001. doi:10.2165/00003495-200161120-00010. PMID 11693466. http://drugs.adisonline.com/pt/re/drugs/abstract.00003495-200161120-00010.htm. Retrieved 2009-06-20.
- ↑ "Manidipine: a review of its use in the management of hypertension". Drugs 64 (17): 1923–1940. 2004. doi:10.2165/00003495-200464170-00011. PMID 15329044. http://drugs.adisonline.com/pt/re/drugs/abstract.00003495-200464170-00011.htm. Retrieved 2009-06-20.
- ↑ "Antihypertensive effect of manidipine". Drugs 65 (Suppl 2): 11–19. 2005. doi:10.2165/00003495-200565002-00003. PMID 16398058. http://drugs.adisonline.com/pt/re/drugs/abstract.00003495-200565002-00003.htm. Retrieved 2009-06-20.
- ↑ "Manidipine-delapril combination in the management of hypertension". Vascular Health and Risk Management 3 (3): 255–263. 2007. PMID 17703633.
- ↑ "Evaluation of manidipine hydrochloride, a new calcium antagonist, in the treatment of hypertensive patients with renal disorders". Current Therapeutic Research 52 (2): 248–253. August 1992. doi:10.1016/S0011-393X(05)80475-8.
- ↑ (in en) Analogue-based Drug Discovery. John Wiley & Sons. 2006. p. 465. ISBN 9783527607495. https://books.google.com/books?id=FjKfqkaKkAAC&pg=PA465.
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