Chemistry:Midaflur
From HandWiki
Short description: Chemical compound
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| Formula | C7H3F12N3 |
| Molar mass | 357.103 g·mol−1 |
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Midaflur (INN; EXP 338) is an extremely stable 3-imidazoline derivative with central skeletal muscle relaxant and sedative properties in humans[1] and other species of mammals, exhibiting consistently high oral bioavailability and a long duration of action. While its pharmacodynamics remain poorly understood, midaflur resembles meprobamate and pentobarbital in terms of observed effects while being considerably more potent.[2]
See also
References
- ↑ "Effect of 5-imino-2,2,4,4-tetrakis (trifluoromethyl) imidazolidine (EXP 338) on spasticity: A quantitative evaluation". Clinical Pharmacology and Therapeutics 9 (4): 448–55. 1967. doi:10.1002/cpt196894448. PMID 4871898.
- ↑ "The pharmacology and toxicology of midaflur". Toxicology and Applied Pharmacology 18 (4): 917–43. April 1971. doi:10.1016/0041-008x(71)90239-0. PMID 5570243.
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