Chemistry:Centalun
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Short description: Chemical compound
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| Formula | C11H12O2 |
| Molar mass | 176.215 g·mol−1 |
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Centalun was developed by Boehringer Ingelheim in 1962[1] and is a psycholeptic drug with hypnotic and sedative effects, via allosteric agonism of the GABAA receptor.[2] It was previously used for sedation in medical procedures such as surgery,[3] orthopedics[4] and gynecology,[5] although it is no longer in clinical use. Despite its history of clinical use, centalun was never incorporated into the CSA and therefore remains unregulated as a drug of abuse.
References
- ↑ "Procédé pour l'obtention d'alkinediols" BE patent 618130
- ↑ "[Experimental Studies on the Psychic Effect of Sedatives Under Normal and Stress Conditions]" (in German). Psychologische Forschung 27: 377–402. June 1964. doi:10.1007/bf00421338. PMID 14233519.
- ↑ "[Pre- and Postoperative Use of Centalun in Surgery]" (in German). Deutsches Medizinisches Journal 15: 470–1. July 1964. PMID 14238754.
- ↑ "[Sedative Therapy with Centalun in Orthopedics]" (in German). Deutsches Medizinisches Journal 15: 493–4. July 1964. PMID 14243120.
- ↑ "[Experiences with Centalun in Obstetrical and Gynecological Patients]" (in German). Medizinische Monatsschrift 18: 131–3. March 1964. PMID 14193290.
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