Chemistry:Selenophos
From HandWiki
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| Names | |
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| Preferred IUPAC name
Se-[2-(Diethylamino)ethyl] O-ethyl ethylphosphonoselenoate | |
| Other names
Seleno-VE[2]
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C10H24NO2PSe | |
| Molar mass | 300.252 g·mol−1 |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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21 μg/kg (mouse, subcutaneous) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Selenophos is an extremely potent organophosphate acetylcholinesterase inhibitor.[3] It is the selenium analog of the VE nerve agent.
See also
References
- ↑ Nachmansohn, David (1 July 1969). "Proteins of Excitable Membranes". The Journal of General Physiology 54 (1): 187–224. doi:10.1085/jgp.54.1.187. PMID 19873642.
- ↑ Mager, Peter P. (1984). Multidimensional pharmacochemistry : design of safer drugs. Orlando: Academic Press. pp. 354. ISBN 978-0-12-465020-6.
- ↑ Akerfeldt, Stig.; Fagerlind, Lars. (January 1967). "Selenophosphorus Compounds as Powerful Cholinesterase Inhibitors". Journal of Medicinal Chemistry 10 (1): 115–116. doi:10.1021/jm00313a032. PMID 6031689.
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