Chemistry:BRL-44408

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Short description: Chemical compound (drug)
BRL-44408
BRL-44408.svg
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC13H17N3
Molar mass215.300 g·mol−1
3D model (JSmol)
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BRL-44408 is a drug used in scientific research which acts as a selective antagonist for the α2A adrenoreceptor.[1] It has been suggested as having potential therapeutic application in the treatment of extrapyramidal side effects produced by some antipsychotic medications.[2]

References

  1. Alberts P (January 1993). "Subtype classification of presynaptic alpha 2-adrenoceptors". General Pharmacology 24 (1): 1–8. doi:10.1016/0306-3623(93)90003-g. PMID 8387042. 
  2. "Therapeutic potential of alpha2 adrenoceptor antagonism for antipsychotic-induced extrapyramidal motor disorders". Neuroscience Letters 454 (2): 143–7. April 2009. doi:10.1016/j.neulet.2009.03.001. PMID 19429072. 

External links