Chemistry:Histidine methyl ester

From HandWiki
Histidine methyl ester
Histidine methyl ester.svg
Names
Other names
Methyl L-histidinate, HME
Identifiers
3D model (JSmol)
957974
ChEBI
ChEMBL
ChemSpider
EC Number
  • 216-109-3
UNII
Properties
C7H11N3O2
Molar mass 169.184 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

File:HDC Active Site Diagram.tif Histidine methyl ester (HME) is an irreversible histidine decarboxylase inhibitor.[1][2][3] It is the methyl ester of histidine.

See also

References

  1. Lane, Roger S; Manning, James M; Snell, Esmond E (2002). "Histidine decarboxylase of lactobacillus 30a: inactivation and active-site labeling by L-histidine methyl ester". Biochemistry 15 (19): 4180–5. doi:10.1021/bi00664a008. PMID 963031. 
  2. Alston, Theodore A; Abeles, Robert H (2002). "Reaction of Lactobacillus histidine decarboxylase with L-histidine methyl ester". Biochemistry 26 (13): 4082–5. doi:10.1021/bi00387a051. PMID 3651438. 
  3. Komori, H; Nitta, Y; Ueno, H; Higuchi, Y (2012). "Structural Study Reveals That Ser-354 Determines Substrate Specificity on Human Histidine Decarboxylase". The Journal of Biological Chemistry 287 (34): 29175–83. doi:10.1074/jbc.M112.381897. PMID 22767596.