Chemistry:Iproclozide

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Short description: Chemical compound
Iproclozide
Iproclozide.svg
Clinical data
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)
  • In general: uncontrolled
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC11H15ClN2O2
Molar mass242.70 g·mol−1
3D model (JSmol)
  (verify)

Iproclozide (trade names Sursum, Sinderesin) is an irreversible and selective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant, but has since been discontinued.[1] It has been known to cause fulminant hepatitis and there have been at least three reported fatalities due to administration of the drug.[2][3]

See also

References

  1. "[Depressive states in a sanatorium milieu and monoamine oxidase inhibitors. (Therapeutic results by the combination of iproclozide and chlordiazepoxide). Apropos of 146 cases]". Journal de Medecine de Lyon 47 (96): 573–586. April 1966. PMID 5930723. 
  2. "Iproclozide fulminant hepatitis. Possible role of enzyme induction". Gastroenterology 75 (3): 492–496. September 1978. doi:10.1016/0016-5085(78)90856-9. PMID 680506. 
  3. Drug-induced liver disease. Informa Health Care. 2003. p. 455. ISBN 0-8247-0811-3.