Chemistry:AGN-2979
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Short description: Chemical compound
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| Formula | C19H28N2O3 |
| Molar mass | 332.444 g·mol−1 |
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AGN-2979 is a glutarimide tryptophan hydroxylase activation inhibitor.[1][2] It shows antidepressant properties in rodent models of depression.[2]
References
- ↑ "The tryptophan hydroxylase activation inhibitor, AGN-2979, decreases regional 5-HT synthesis in the rat brain measured with alpha-[14C]methyl-L-tryptophan: an autoradiographic study". Brain Research Bulletin 67 (3): 248–55. October 2005. doi:10.1016/j.brainresbull.2005.07.009. PMID 16144662.
- ↑ 2.0 2.1 "Antidepressant-like action of AGN 2979, a tryptophan hydroxylase activation inhibitor, in a chronic mild stress model of depression in rats". European Neuropsychopharmacology 11 (5): 351–7. October 2001. doi:10.1016/S0924-977X(01)00103-1. PMID 11597821.
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