Chemistry:Sercloremine
From HandWiki
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| Preferred IUPAC name
4-(5-Chloro-1-benzofuran-2-yl)-1-methylpiperidine | |
| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C14H16ClNO | |
| Molar mass | 249.74 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Sercloremine (CGP-4718A), usually as the hydrochloride salt, is a drug which was developed in the 1980s and was formerly under investigation as an antidepressant, but was never marketed.[1][2] It acts as a selective, reversible inhibitor of monoamine oxidase A (RIMA) and serotonin reuptake inhibitor.[1][3]
References
- ↑ 1.0 1.1 "Antidepressant agents". Annual Reports in Medicinal Chemistry. 22. Academic Press. January 1987. pp. 21–30 (25). ISBN 978-0-08-058366-2. https://books.google.com/books?id=oJeTSJveeuAC&pg=PA25.
- ↑ Dictionary of Pharmacological Agents. CRC Press. 21 November 1996. pp. 1801–. ISBN 978-0-412-46630-4. https://books.google.com/books?id=A0THacd46ZsC&pg=PA1801.
- ↑ "Early experience with CGP 4718 A (Sercloremine), a new selective and reversible MAO-A and 5-HT-uptake inhibitor, in the treatment of depressive patients". Drug Development Research 6 (4): 371–384. 1985. doi:10.1002/ddr.430060409. ISSN 0272-4391.
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