Chemistry:CX157
From HandWiki
Short description: Chemical compound
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| Routes of administration | Oral |
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| Formula | C14H8F4O4S |
| Molar mass | 348.27 g·mol−1 |
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CX157 (proposed trade name TriRima, formerly Tyrima) is a selective and reversible inhibitor of MAO-A (RIMA).[1] As of 2007 it was in phase II clinical trials for the treatment of depression.[2] In 2013, work on the drug was terminated.[1]
References
- ↑ "Pharmacokinetics and oral bioavailability of CX157, a reversible selective MAO-A inhibitor, in primates". 2007 AAPS Annual Meeting & Exposition. 2007. http://www.aapsj.org/abstracts/AM_2007/AAPS2007-001233.PDF. Retrieved 2009-06-14.
- ↑ Clinical trial number NCT00739908} for "A Study of CX157 (TriRima) for the Treatment of Depression (CX157-200)" at ClinicalTrials.gov
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