Chemistry:Erbulozole

Short description: Chemical compound

Erbulozole

Clinical data
Other names	Erbuzole
Identifiers
CAS Number	124784-31-2
PubChem CID	9934372
ChemSpider	8110000
UNII	78XGN2K5RX
Chemical and physical data
Formula	C24H27N3O5S
Molar mass	469.56 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCOC(=O)NC1=CC=C(C=C1)SC[C@H]2CO[C@](O2)(CN3C=CN=C3)C4=CC=C(C=C4)OC
InChI InChI=1S/C24H27N3O5S/c1-3-30-23(28)26-19-6-10-22(11-7-19)33-15-21-14-31-24(32-21,16-27-13-12-25-17-27)18-4-8-20(29-2)9-5-18/h4-13,17,21H,3,14-16H2,1-2H3,(H,26,28)/t21-,24+/m1/s1 Key:KLEPCGBEXOCIGS-QPPBQGQZSA-N
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Erbulozole (R55104) is a congener of the microtubule inhibitor tubulozole. It is undergoing phase I clinical trials as a chemotherapeutic agent.

Synthesis

Erbulozole synthesis: Lednicer book 6 (Drugs of the Future citation).

Other reading

• "Erbulozole. Antineoplastic, Microtubule inhibitor". Drugs Future 16 (6): 577. 1991.