Chemistry:Gestaclone

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Gestaclone (INN, USAN) (developmental code name SH-1040), also known as 6-chloro-1α,2α:16α,17-bismethylene-4,6-pregnadiene-3,20-dione, is a steroidal progestin of unique chemical structure derived from progesterone that was first described in 1967 and was never marketed.[1]

Synthesis

Synthesis:[2] Patent:[3][4]

References

  1. ↑ The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. p. 595. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA595. 
  2. ↑ The organic chemistry of drug synthesis. 2. Wiley. 1980. p. 168. ISBN 978-0-471-04392-8. 
  3. ↑ Neumann F, Wiechert R, "1,2-alpha,16,17-alpha-bismethylene-delta-4,6-pregnadienes", US patent 3441647, issued 1969-04-29, assigned to Schering AGand Bayer Pharma AG
  4. ↑ Gries H, Heinz J, "Process for the production of α,β-methylene ketones of the steriod series", DE patent 1286033, published 1969-01-02, assigned to Schering AGand Bayer Pharma AG




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