Chemistry:ZM-182345

From HandWiki
Short description: Chemical compound
ZM-182345
ZM-182345.svg
Identifiers
PubChem CID
Chemical and physical data
FormulaC19H16F6N2O4
Molar mass450.337 g·mol−1
3D model (JSmol)

ZM-182345 is a nonsteroidal progestin that was never marketed.[1][2] It was derived from structural modification of the nonsteroidal antiandrogen hydroxyflutamide.[1][2] ZM-182345 was found to be at least as potent as progesterone as a progestogen in animals but to also possess androgenic activity.[1]

References

  1. 1.0 1.1 1.2 "Nonsteroidal progestins and antiprogestins related to flutamide". Steroids 65 (10–11): 725–31. 2000. doi:10.1016/s0039-128x(00)00179-3. PMID 11108883. 
  2. 2.0 2.1 "Progesterone receptor: overview of modern steroidal progestins and developments in the field of nonsteroidal selective progesterone receptor modulators.". Nuclear Receptors as Drug Targets. John Wiley & Sons. 8 September 2008. pp. 209–. ISBN 978-3-527-62330-3. https://books.google.com/books?id=iATfLbPgRugC&pg=PA209.