Chemistry:Segesterone
From HandWiki
Short description: Chemical compound
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| Other names | 17α-Hydroxy-16-methylene-19-norprogesterone; 16-Methylene-17α-hydroxy-19-norpregn-4-ene-3,20-dione; 17α-Deacetylnestorone |
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| Formula | C21H28O3 |
| Molar mass | 328.452 g·mol−1 |
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Segesterone (INN, USAN),[1][2] also known as 17α-hydroxy-16-methylene-19-norprogesterone or as 17α-deacetylnestorone, is a steroidal progestin of the 19-norprogesterone group that was never marketed.[3] An acetate ester, segesterone acetate, better known as nestorone or elcometrine, is marketed for clinical use.[4] Segesterone acetate produces segesterone as a metabolite.[5]
References
- ↑ International Nonproprietary Names for Pharmaceutical Substances (INN). 17. World Health Organization. 2003. pp. 210. https://www.who.int/medicines/publications/druginformation/innlists/PL89.pdf.
- ↑ "7690-08-6 - SFLXYFZGKSGFKA-XUDSTZEESA-N - Segesterone [USAN:INN] - Similar structures search, synonyms, formulas, resource links, and other chemical information". ChemIDplus. U.S. National Library of Medicine. https://chem.nlm.nih.gov/chemidplus/rn/7690-08-6.
- ↑ "Segesterone". PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/11823650.
- ↑ "Chapter 41: Women's Health". Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. 24 January 2012. pp. 1403–. ISBN 978-1-60913-345-0. https://books.google.com/books?id=Sd6ot9ul-bUC&pg=PA1403.
- ↑ "Single-dose pharmacokinetics of Nestorone, a potential female-contraceptive". Steroids 75 (3): 252–264. March 2010. doi:10.1016/j.steroids.2009.12.011. PMID 20064539.
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