Chemistry:Clogestone acetate
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Short description: Chemical compound
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| Other names | Chlormadinol acetate; AY-11440; 3β,17α-Diacetoxy-6-chloropregna-4,6-diene-20-one |
| Drug class | Progestogen; Progestogen ester |
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| Formula | C25H33ClO5 |
| Molar mass | 448.98 g·mol−1 |
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Clogestone acetate (USAN) (developmental code name AY-11440), also known as chlormadinol acetate or as 3β,17α-diacetoxy-6-chloropregna-4,6-diene-20-one,[1] is a steroidal progestin which was investigated as a progestin-only contraceptive and postcoital contraceptive but was never marketed.[2][3][4][5] It is the diacetate ester of clogestone, which, similarly was never marketed.[2] Clogestone acetate produces chlormadinone acetate as an active metabolite.[6]
See also
References
- ↑ Biochemical Actions of Hormones. Elsevier. 2 December 2012. pp. 323–. ISBN 978-0-323-15189-4. https://books.google.com/books?id=et3Lq-TitzAC&pg=PA323.
- ↑ 2.0 2.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 297–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA297.
- ↑ Human Fertility Control: Theory and Practice. Elsevier Science. 22 October 2013. pp. 3–. ISBN 978-1-4831-6361-1. https://books.google.com/books?id=1lL0AgAAQBAJ&pg=PA3.
- ↑ "Contraception — retrospect and prospect". Progress in Drug Research, vol. 21. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des rechersches pharmaceutiques. 21. Birkhäuser. 8 March 2013. pp. 293–407. doi:10.1007/978-3-0348-7098-6_4. ISBN 978-3-0348-7098-6. https://books.google.com/books?id=VFb2BwAAQBAJ&pg=PA321.
- ↑ "[Clogestone acetate, a new orally effective progestagen]" (in de). Archiv Fur Gynakologie 209 (2): 136–148. August 1970. doi:10.1007/BF00668180. PMID 5537778.
- ↑ "Measurement of serum clogestone acetate (AY-11,440) by a radioreceptor assay: a practical approach to the quantitative determination of synthetic progestins". The Journal of Clinical Endocrinology and Metabolism 40 (4): 728–731. April 1975. doi:10.1210/jcem-40-4-728. PMID 1127082.
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