Chemistry:Megestrol

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Short description: Chemical compound
Megestrol
Megestrol.svg
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
Chemical and physical data
FormulaC22H30O3
Molar mass342.479 g·mol−1
3D model (JSmol)
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Megestrol (INN, BAN) is a progestin of the 17α-hydroxyprogesterone group which was never marketed and is not currently used clinically.[1][2] Its acylated derivative megestrol acetate is also a progestogen, which, in contrast to megestrol itself, has been extensively used as a pharmaceutical drug.[1][2]

Synthesis

Megestrol synthesis:[3] U.S. Patent 2,891,079

See also

References

  1. 1.0 1.1 Dictionary of Pharmacological Agents. CRC Press. 1997. p. 1267. ISBN 978-0-412-46630-4. https://books.google.com/books?id=A0THacd46ZsC&pg=PA1267. Retrieved 12 May 2012. 
  2. 2.0 2.1 Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 641. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA641. Retrieved 28 May 2012. 
  3. "Steroids. CXVIII.16-Methyl Derivatives of 17α-Hydroxyprogesterone and of Reichstein's Substance "S"". Journal of the American Chemical Society 81 (14): 3712–3716. 1959. doi:10.1021/ja01523a055.