Chemistry:Medroxyprogesterone caproate

From HandWiki
Short description: Chemical compound
Medroxyprogesterone caproate
Medroxyprogesterone caproate.svg
Clinical data
Other namesMPC; Medroxyprogesterone capronate; Medroxyprogesterone hexanoate; 6α-Methyl-17α-hydroxyprogesterone hexanoate; 6α-Methyl-17α-hydroxypregn-4-ene-3,20-dione hexanoate
Routes of
administration		Intramuscular injection
Drug classProgestogen; Progestin; Progestogen ester
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC28H42O4
Molar mass442.640 g·mol−1
3D model (JSmol)

Medroxyprogesterone caproate (MPC) is a progestin and a progestogen ester which was synthesized in 1958 but was never marketed.[1][2] It has been confused with hydroxyprogesterone caproate (OHPC) and medroxyprogesterone acetate (MPA) in a number of publications.[3][4][5][6][7][8][9][10][11][12] In addition to MPA and OHPC, analogues of MPC include chlormadinone caproate, gestonorone caproate, megestrol caproate, and methenmadinone caproate.

See also

References

  1. ↑ "6α-Methyl-17α-hydroxyprogesterone 17-acylates; a new class of potent progestins". Journal of the American Chemical Society 80 (11): 2904–2905. 1958. doi:10.1021/ja01544a079. ISSN 0002-7863. 
  2. ↑ "510. Photochemical transformations. Part IV. The photochemistry of prednisone acetate". Journal of the Chemical Society (Resumed): 2500–2510. 1958. doi:10.1039/jr9580002500. ISSN 0368-1769. 
  3. ↑ "Progestins and breast cancer". The Journal of Steroid Biochemistry and Molecular Biology 65 (1–6): 225–235. April 1998. doi:10.1016/S0960-0760(98)00028-4. PMID 9699877. 
  4. ↑ "Biological effects of progestins in breast cancer". Gynecological Endocrinology 13 (Suppl 4): 11–19. June 1999. doi:10.1080/gye.13.s4.11.19. PMID 12227897. 
  5. ↑ "Biological responses of progestogen metabolites in normal and cancerous human breast". Hormone Molecular Biology and Clinical Investigation 3 (3): 427–435. December 2010. doi:10.1515/HMBCI.2010.066. PMID 25961215. 
  6. ↑ "Estradiol and progesterone receptors in two cases of endometrial stromal sarcoma". Gynecologic Oncology 18 (2): 233–239. June 1984. doi:10.1016/0090-8258(84)90031-3. PMID 6735266. 
  7. ↑ Female genital cancer. Churchill Livingstone. 1988. p. 374. ISBN 978-0-443-08525-3. https://books.google.com/books?id=DKNrAAAAMAAJ. 
  8. ↑ Proceedings. American Cancer Society and National Cancer Institute of the U.S. Public Health Service, Federal Security Agency.. 1970. p. 376. https://books.google.com/books?id=yJQRAQAAMAAJ. 
  9. ↑ Ambulatory Gynecology. Harper & Row. 1985. p. 518. ISBN 978-0-06-141815-0. https://books.google.com/books?id=zMZsAAAAMAAJ. 
  10. ↑ Goodman & Gilman's the Pharmacological Basis of Therapeutics. McGraw-Hill, Health Professions Division. 1996. pp. 1427,1823,1858. ISBN 978-0-07-026266-9. https://books.google.com/books?id=09h_hZiYXgUC. 
  11. ↑ Endokrinologie. Johann Ambrosius Barth Verlag.. 1969. p. 431. https://books.google.com/books?id=8ZW3AAAAIAAJ. 
  12. ↑ "Failure of medroxyprogesterone caproate to maintain pregnancy in ovariectomised mares.". Equine Vet J 25 (2): 158–160. 1993. doi:10.1111/j.2042-3306.1993.tb02928.x. PMID 8467776. 



Retrieved from "https://handwiki.org/wiki/index.php?title=Chemistry:Medroxyprogesterone_caproate&oldid=3339422"