Chemistry:Ro 6-3129
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Short description: Chemical compound
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| Other names | 16α-Ethylthiodydrogesterone; 16α-Ethylthio-6-dehydroretroprogesterone; 16α-Ethylthio-9β,10α-pregna-4,6-diene-3,20-dione |
| Routes of administration | Oral |
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| Formula | C23H32O2S |
| Molar mass | 372.57 g·mol−1 |
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Ro 6-3129, also known as 16α-ethylthio-6-dehydroretroprogesterone or as 16α-ethylthio-9β,10α-pregna-4,6-diene-3,20-dione, as well as 16α-ethylthiodydrogesterone, is a progestogen of the retroprogesterone group which was developed by Roche but was never marketed.[1][2][3] It shows greater potency than dydrogesterone in bioassays.[4]
References
- ↑ "Contraception — retrospect and prospect". Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des rechersches pharmaceutiques. 21. 1977. pp. 293–407 (321). doi:10.1007/978-3-0348-7098-6_4. ISBN 978-3-0348-7098-6. https://books.google.com/books?id=VFb2BwAAQBAJ&pg=PA321.
- ↑ "Effects of daily administration of a retrosteroid on the plasma levels of progesterone and on the urinary excretion of luteinizing hormone and total oestrogens". The Journal of Obstetrics and Gynaecology of the British Commonwealth 77 (9): 840–846. September 1970. doi:10.1111/j.1471-0528.1970.tb04411.x. PMID 5458777.
- ↑ "Pharmacokinetics of the retro-steroid progestogen, 16α-ethylthio-9β,10α-pregna-4, 6-diene-3, 20-dione (Ro 6-3129), in man and the sheep". Contraception 8 (1): 53–65. 1973. doi:10.1016/0010-7824(73)90159-5. ISSN 0010-7824.
- ↑ The Journal of Obstetrics and Gynaecology of the British Commonwealth. Royal College of Obstetricians and Gynaecologists. 1970. https://books.google.com/books?id=_gtA33qrWkIC.
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