Chemistry:19-Nor-5-androstenedione
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| Other names | Estr-5-ene-3,17-dione; 19-Norandrost-5-ene-3,17-dione |
| Routes of administration | Oral |
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| Formula | C18H24O2 |
| Molar mass | 272.388 g·mol−1 |
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19-Nor-5-androstenedione, also known as estr-5-ene-3,17-dione, is a synthetic, orally active anabolic-androgenic steroid (AAS) and a derivative of 19-nortestosterone (nandrolone) that was never introduced for medical use.[1][2][3] It is an androgen prohormone of nandrolone and of other 19-norandrostanes.[1][2][3]
19-Nor-5-androstenedione, 19-nor-5-androstenediol, and other 19-norandrostane prohormones were considered to be nutritional supplements and were sold over-the-counter in the United States as a result of the Dietary Supplement Health and Education Act of 1994 (DSHEA).[1][2] However, they were banned from sports in 1999 by the International Olympic Committee (IOC) and are currently on the World Anti-Doping Agency (WADA) list of prohibited substances.[1] In 2004, they became controlled substances in the U.S. as a result of the Anabolic Steroid Control Act of 2004.[1]
See also
- 5-Androstenedione
- Bolandiol (19-nor-4-androstenediol)
- Bolandione (19-nor-4-androstenedione)
- Bolenol (17α-ethyl-19-nor-5-androstenol)
- Chlorodehydromethylandrostenediol
- Chloromethylandrostenediol
- Methandriol (17α-methyl-5-androstenediol)
References
- ↑ 1.0 1.1 1.2 1.3 1.4 "Urinary metabolic profile of 19-norsteroids in humans: glucuronide and sulphate conjugates after oral administration of 19-nor-4-androstenediol". Rapid Commun. Mass Spectrom. 22 (19): 3035–42. 2008. doi:10.1002/rcm.3689. PMID 18763272. Bibcode: 2008RCMS...22.3035T.
- ↑ 2.0 2.1 2.2 "Over-the-counter delta5 anabolic steroids 5-androsen-3,17-dione; 5-androsten-3beta, 17beta-diol; dehydroepiandrosterone; and 19-nor-5-androsten-3,17-dione: excretion studies in men". J Anal Toxicol 24 (3): 188–93. 2000. doi:10.1093/jat/24.3.188. PMID 10774538.
- ↑ 3.0 3.1 "Dietary androgen 'supplements': separating substance from hype". Phys Sportsmed 29 (5): 63–79. 2001. doi:10.3810/psm.2001.05.781. PMID 20086575.
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