Chemistry:Lysophosphatidylinositol
From HandWiki
| |
| Names | |
|---|---|
| IUPAC name
[(2R)-2-hydroxy-3-[hydroxy-[(2R,3R,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]-oxyphosphoryl]oxypropyl] hexadecanoate
| |
| Identifiers | |
3D model (JSmol)
|
|
PubChem CID
|
|
| |
| Properties | |
| C25H49O12P | |
| Molar mass | 572.629 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
Lysophosphatidylinositol (LPI, lysoPI), or L-α-lysophosphatidylinositol, is an endogenous lysophospholipid and endocannabinoid neurotransmitter.[1] LPI, along with its 2-arachidonoyl- derivative, 2-arachidonoyl lysophosphatidylinositol (2-ALPI), have been proposed as the endogenous ligands of GPR55.[2][3][4][5]
See also
References
- ↑ "Lysophospholipids induce innate immune transdifferentiation of endothelial cells, resulting in prolonged endothelial activation.". The Journal of Biological Chemistry 293 (28): 11033–11045. May 2018. doi:10.1074/jbc.RA118.002752. PMID 29769317.
- ↑ "Identification of GPR55 as a lysophosphatidylinositol receptor". Biochemical and Biophysical Research Communications 362 (4): 928–34. November 2007. doi:10.1016/j.bbrc.2007.08.078. PMID 17765871.
- ↑ "The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation". The FASEB Journal 23 (1): 183–93. January 2009. doi:10.1096/fj.08-108670. PMID 18757503.
- ↑ Piñeiro, Roberto; Falasca, Marco (2012). "Lysophosphatidylinositol signalling: New wine from an old bottle". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1821 (4): 694–705. doi:10.1016/j.bbalip.2012.01.009. PMID 22285325. https://zenodo.org/record/895487.
- ↑ "2-Arachidonoyl-sn-glycero-3-phosphoinositol: a possible natural ligand for GPR55". Journal of Biochemistry 145 (1): 13–20. January 2009. doi:10.1093/jb/mvn136. PMID 18845565.
 |  |
