Chemistry:CBS-0550
From HandWiki
Short description: Chemical compound
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| Formula | C20H23F4N3O |
| Molar mass | 397.418 g·mol−1 |
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CBS-0550 is a drug developed by Taisho Pharmaceutical, which acts as a potent and selective cannabinoid CB2 receptor agonist, with 1400x selectivity for CB2 over the related CB1 receptor. Unlike most cannabinoid agonists, CBS-0550 has good solubility in water, and in animal studies it was found to produce analgesic and anti-hyperalgesic effects.[1] A number of related compounds have been developed with similar properties.[2]
See also
References
- ↑ "Imine derivatives as new potent and selective CB2 cannabinoid receptor agonists with an analgesic action". Bioorganic & Medicinal Chemistry 16 (3): 1111–24. February 2008. doi:10.1016/j.bmc.2007.10.087. PMID 18006322.
- ↑ "N-Alkylidenearylcarboxamides as new potent and selective CB(2) cannabinoid receptor agonists with good oral bioavailability". Bioorganic & Medicinal Chemistry Letters 17 (22): 6299–304. November 2007. doi:10.1016/j.bmcl.2007.09.004. PMID 17884496.
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