Chemistry:JZL195

From HandWiki
JZL195
Names
Preferred IUPAC name
4-Nitrophenyl 4-[(3-phenoxyphenyl)methyl]piperazine-1-carboxylate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
Properties
C24H23N3O5
Molar mass 433.464 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

JZL195 is a potent inhibitor of both fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), the primary enzymes responsible for degrading the endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG), respectively.[1]

See also

References

  1. ↑ "Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo". Proceedings of the National Academy of Sciences of the United States of America 106 (48): 20270–5. December 2009. doi:10.1073/pnas.0909411106. PMID 19918051. Bibcode: 2009PNAS..10620270L.