Chemistry:11-Dehydroprogesterone
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Short description: Chemical compound
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| Other names | Pregna-4,11-diene-3,20-dione |
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| Formula | C21H28O2 |
| Molar mass | 312.453 g·mol−1 |
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11-Dehydroprogesterone, also known as pregna-4,11-diene-3,20-dione, is a steroidal progestin that was never marketed.[1][2][3] It was found to be 2- to 3-fold as potent as progesterone as a progestogen in animal bioassays,[1][4] although other studies found them to be equivalent in potency.[2] 11-Dehydroprogesterone has been studied in women.[5] It was discovered in the 1930s or 1940s, and was one of the earliest synthetic progestogens.[3]
See also
References
- ↑ 1.0 1.1 "Comparative potency of several progestogenic compounds in a battery of different biological tests". Annals of the New York Academy of Sciences 71 (5): 532–541. July 1958. doi:10.1111/j.1749-6632.1958.tb46783.x. PMID 13583809. Bibcode: 1958NYASA..71..532Z.
- ↑ 2.0 2.1 "Biological activity of certain progesterone-like compounds as determined by the Hooker-Forbes bioassay". The Journal of Clinical Endocrinology and Metabolism 17 (5): 658–666. May 1957. doi:10.1210/jcem-17-5-658. PMID 13416376.
- ↑ 3.0 3.1 "The Chemistry of the Hormones". Annual Review of Biochemistry 11 (1): 283–308. 1942. doi:10.1146/annurev.bi.11.070142.001435. ISSN 0066-4154.
- ↑ "High progestational activity of 19-norprogesterone". Endocrinology 52 (3): 359–361. March 1953. doi:10.1210/endo-52-3-359. PMID 13033848.
- ↑ "[Effects of 11-dehydroprogesterone in women]". Annales d'Endocrinologie 11 (2): 179–182. 1950. PMID 14799957. (in Undetermined Language)
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