Chemistry:Pentarane A

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Short description: Chemical compound
Pentarane A
Pentarane A.svg
Clinical data
Other namesD'6-Pentarane; Pregna-D'6-pentarane; 16α,17α-Cyclohexanoprogesterone; 16α,17α-Tetramethylenepregn-4-ene-3,20-dione; 17α-Acetyl-16β,24-cyclo-21-norchol-4-en-3-one
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC25H36O2
Molar mass368.561 g·mol−1
3D model (JSmol)

Pentarane A, also known as D'6-pentarane or pregna-D'6-pentarane, as well as 16α,17α-cyclohexanoprogesterone, 16α,17α-tetramethylenepregn-4-ene-3,20-dione, or 17α-acetyl-16β,24-cyclo-21-norchol-4-en-3-one, is a steroidal progestin that was developed by the Zelinskii Institute of Organic Chemistry of the Russian Academy of Sciences and was never marketed.[1][2] The 6α-methylated analogue of pentarane A is known as mecigestone or as pentarane B.[2]

See also

References

  1. "Pregna-D'-pentaranes - a new class of active gestagenes". Journal of Steroid Biochemistry 16 (1): 61–67. January 1982. doi:10.1016/0022-4731(82)90144-3. PMID 7062740. 
  2. 2.0 2.1 "Interaction of cycloalkanoprogesterones with mammalian progesterone receptor: binding of pregna-D'-pentaranes in the calf uterine cytosol". Molecular and Cellular Biochemistry 125 (2): 153–161. August 1993. doi:10.1007/BF00936444. PMID 8283970.