Chemistry:17α-Methyl-19-norprogesterone
From HandWiki
Short description: Chemical compound
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| Other names | H-3510; 17α-Methyl-19-norpregn-4-ene-3,20-dione; (17β)-17-Acetyl-17-methylestr-4-en-3-one |
| Drug class | Progestin; Progestogen |
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| Chemical and physical data | |
| Formula | C21H30O2 |
| Molar mass | 314.469 g·mol−1 |
| 3D model (JSmol) | |
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17α-Methyl-19-norprogesterone (developmental code name H-3510), also known as 17α-methyl-19-norpregn-4-ene-3,20-dione, is a progestin which was never marketed.[1][2][3] It is a derivative of progesterone, and is the combined derivative of 17α-methylprogesterone and 19-norprogesterone.[1] The drug is the parent compound of a subgroup of the 19-norprogesterone group of progestins, which includes demegestone (the δ9 derivative), promegestone (the δ9 and 21-methyl derivative), and trimegestone (the δ9, 21-methyl, and 21-hydroxyl derivative).[4]
See also
- Gestronol (17α-hydroxy-19-norprogesterone)
References
- ↑ 1.0 1.1 "The formation of steroid enolate anions by reductive procedures". Tetrahedron 20 (2): 357–372. 1964. doi:10.1016/S0040-4020(01)93223-5. ISSN 0040-4020.
- ↑ Elsimar Coutinho, ed (1974). "Progesterone-Progestin Receptors". Physiology and Genetics of Reproduction, part A. Basic Life Sciences. 4. pp. 143–160. doi:10.1007/978-1-4684-2889-6_10. ISBN 978-1-4684-2891-9.
- ↑ "Steroid flexibility and receptor specificity". Journal of Steroid Biochemistry 13 (1): 45–59. January 1980. doi:10.1016/0022-4731(80)90112-0. PMID 7382482.
- ↑ "Pharmacology of estrogens and progestogens: influence of different routes of administration". Climacteric 8 (Suppl 1): 3–63. August 2005. doi:10.1080/13697130500148875. PMID 16112947.
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