Chemistry:Prenderol
From HandWiki
Short description: Chemical compound
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| Formula | C7H16O2 |
| Molar mass | 132.203 g·mol−1 |
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| Melting point | 59–62 °C (138–144 °F) |
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Prenderol (Diethylpropanediol) is a simple alkyl diol which has sedative, anticonvulsant and muscle relaxant effects. It is closely related in structure to meprobamate and numerous other alkyl alcohols and diols with generally comparable activity.[1][2][3][4][5][6]
See also
- 1,4-Butanediol
- 1,6-Dioxecane-2,7-dione
- 1-Ethynylcyclohexanol
- 2-Methyl-2-propyl-1,3-propanediol
- 2-Methyl-2-butanol
- 2-Methyl-2-pentanol
- 3-Methyl-3-pentanol
- 3-Hydroxybutanal
- Ethchlorvynol
- Phenaglycodol
References
- ↑ "Anticonvulsant action of 2-substituted-1,3-propanediols". Proceedings of the Society for Experimental Biology and Medicine (New York, N.Y.) 71 (2): 270–271. June 1949. doi:10.3181/00379727-71-17159. PMID 18134033.
- ↑ "Site of action of 2, 2-diethyl-1,3-propanediol (prenderol) on the central nervous system". The Journal of Pharmacology and Experimental Therapeutics 107 (3): 344–55. March 1953. PMID 13035673. https://jpet.aspetjournals.org/content/107/3/344.short.
- ↑ "Effects of mephenesin and prenderol on intellectual functions of mental patients". Journal of Clinical Psychology 10 (3): 283–5. July 1954. doi:10.1002/1097-4679(195407)10:3<283::aid-jclp2270100322>3.0.co;2-a. PMID 13163224.
- ↑ "Head shaking and nystagmus produced by 2,2-diethyl, 1,3-propanediol (prenderol) in the rat". Archives Internationales de Pharmacodynamie et de Therapie 137: 128–36. May 1962. PMID 13870189.
- ↑ Reyes Q., Aaurelio; Mascetti V., G.; Martinez J., Rolando. Synthesis of polyhydroxylated alcohols. Revista Latinoamericana de Quimica 1984; 15 (1): 29-30. ISSN: 0370-5943.
- ↑ "A nitrate ester of sedative alkyl alcohol improves muscle function and structure in a murine model of Duchenne muscular dystrophy". Molecular Pharmaceutics 10 (10): 3862–70. October 2013. doi:10.1021/mp400310r. PMID 23924275.
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