Chemistry:Medroxyprogesterone caproate
From HandWiki
Short description: Chemical compound
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| Other names | MPC; Medroxyprogesterone capronate; Medroxyprogesterone hexanoate; 6α-Methyl-17α-hydroxyprogesterone hexanoate; 6α-Methyl-17α-hydroxypregn-4-ene-3,20-dione hexanoate |
| Routes of administration | Intramuscular injection |
| Drug class | Progestogen; Progestin; Progestogen ester |
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| Formula | C28H42O4 |
| Molar mass | 442.640 g·mol−1 |
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Medroxyprogesterone caproate (MPC) is a progestin and a progestogen ester which was synthesized in 1958 but was never marketed.[1][2] It has been confused with hydroxyprogesterone caproate (OHPC) and medroxyprogesterone acetate (MPA) in a number of publications.[3][4][5][6][7][8][9][10][11][12] In addition to MPA and OHPC, analogues of MPC include chlormadinone caproate, gestonorone caproate, megestrol caproate, and methenmadinone caproate.
See also
References
- ↑ "6α-Methyl-17α-hydroxyprogesterone 17-acylates; a new class of potent progestins". Journal of the American Chemical Society 80 (11): 2904–2905. 1958. doi:10.1021/ja01544a079. ISSN 0002-7863.
- ↑ "510. Photochemical transformations. Part IV. The photochemistry of prednisone acetate". Journal of the Chemical Society (Resumed): 2500–2510. 1958. doi:10.1039/jr9580002500. ISSN 0368-1769.
- ↑ "Progestins and breast cancer". The Journal of Steroid Biochemistry and Molecular Biology 65 (1–6): 225–235. April 1998. doi:10.1016/S0960-0760(98)00028-4. PMID 9699877.
- ↑ "Biological effects of progestins in breast cancer". Gynecological Endocrinology 13 (Suppl 4): 11–19. June 1999. doi:10.1080/gye.13.s4.11.19. PMID 12227897.
- ↑ "Biological responses of progestogen metabolites in normal and cancerous human breast". Hormone Molecular Biology and Clinical Investigation 3 (3): 427–435. December 2010. doi:10.1515/HMBCI.2010.066. PMID 25961215.
- ↑ "Estradiol and progesterone receptors in two cases of endometrial stromal sarcoma". Gynecologic Oncology 18 (2): 233–239. June 1984. doi:10.1016/0090-8258(84)90031-3. PMID 6735266.
- ↑ Female genital cancer. Churchill Livingstone. 1988. p. 374. ISBN 978-0-443-08525-3. https://books.google.com/books?id=DKNrAAAAMAAJ.
- ↑ Proceedings. American Cancer Society and National Cancer Institute of the U.S. Public Health Service, Federal Security Agency.. 1970. p. 376. https://books.google.com/books?id=yJQRAQAAMAAJ.
- ↑ Ambulatory Gynecology. Harper & Row. 1985. p. 518. ISBN 978-0-06-141815-0. https://books.google.com/books?id=zMZsAAAAMAAJ.
- ↑ Goodman & Gilman's the Pharmacological Basis of Therapeutics. McGraw-Hill, Health Professions Division. 1996. pp. 1427,1823,1858. ISBN 978-0-07-026266-9. https://books.google.com/books?id=09h_hZiYXgUC.
- ↑ Endokrinologie. Johann Ambrosius Barth Verlag.. 1969. p. 431. https://books.google.com/books?id=8ZW3AAAAIAAJ.
- ↑ "Failure of medroxyprogesterone caproate to maintain pregnancy in ovariectomised mares.". Equine Vet J 25 (2): 158–160. 1993. doi:10.1111/j.2042-3306.1993.tb02928.x. PMID 8467776.
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