Chemistry:EA-1356

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EA-1356
EA-1356 Structure.svg
Names
Preferred IUPAC name
2-Methylcyclohexyl methylphosphonofluoridate
Identifiers
3D model (JSmol)
ChemSpider
Properties
C8H16FO2P
Molar mass 194.186 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

EA-1356 is an organophosphate nerve agent of the G-series.[1][2] It is highly resistant to enzymatic degradation in the body. [3] The nerve agent was tested at Edgewood Arsenal in Maryland (the "EA" in "Ea-1356") among many other chemicals tested on humans. A novel enzyme was patented by the US Army in 2018 to break down EA-1356. It is a schedule 1 substance by the Chemical Weapons Convention standards. It is under the category of munitions of ML7.b.1.a.

References

  1. "Identification of some nerve agent homologues and dialkyl methylphosphonates by gas chromatography/Fourier transform infrared spectrometry.". Fresenius' Journal of Analytical Chemistry 352 (6): 550–556. 1995. doi:10.1007/BF00323072. 
  2. Ellison, D. Hank (2008). Handbook of Chemical and Biological Warfare Agents (Second ed.). CRC Press. ISBN 978-0-849-31434-6. 
  3. Harvey SP, Guelta MA, McMahon LR, "Mutant OPAA enzymes with increased catalytic efficiency on organophosphorus compound EA1356", US patent 10124043, issued 13 November 2018, assigned to U.S. Army Edgewood Chemical Biological Center