Chemistry:MSPI (nerve agent)
From HandWiki
| |
| Names | |
|---|---|
| Other names
MSMPID
| |
| Identifiers | |
3D model (JSmol)
|
|
| ChemSpider | |
PubChem CID
|
|
| |
| |
| Properties | |
| C5H9N2O2PS | |
| Molar mass | 192.17 g·mol−1 |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
|
3.15 mg/kg (mice, subcutaneous) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
MSPI is an irreversible acetylcholinesterase inhibitor. MSPI reacts with the acetylcholinesterase to form an aged enzyme adduct that can't be reactivated by cholinesterase reactivators.[1]
See also
References
- ↑ Chabrier, P. E.; Jacob, J. (May 1980). "In vivo and in vitro inhibition of cholinesterase by methyl-1 (S methyl phosphoryl-3) imidazolium (MSPI), a model of an "instantly" aged phosphorylated enzyme". Archives of Toxicology 45 (1): 15–20. doi:10.1007/BF00303290. PMID 7396718.
 |  |
