Chemistry:Trimetozine

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Short description: Chemical compound
Trimetozine
Trimetozine.svg
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC14H19NO5
Molar mass281.308 g·mol−1
3D model (JSmol)

Trimetozine (Opalene, Trimolide, Trioxazine) is a sedative that has been marketed in Europe since 1959.[1][2] It also has mild tranquilizing effects and has been used in the treatment of anxiety.[3][4] Its mechanism of action is unclear.[citation needed]

Conversion of the amide in trimetozine to the thioamide gives Tritiozine.

References

  1. Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. pp. 1932. ISBN 3-88763-075-0. https://books.google.com/books?id=5GpcTQD_L2oC&q=trimetozine&pg=PA1067. 
  2. David J. Triggle (1997). Dictionary of pharmacological agents. London: Chapman & Hall. ISBN 0-412-46630-9. https://books.google.com/books?id=A0THacd46ZsC&q=trimetozine&pg=PA2065. 
  3. "[Clinical trial of a new tranquilizing agent: trioxazine]" (in it). Minerva Medica 61 (46): 2574–90. June 1970. PMID 5425739. 
  4. "[Trioxazine in the treatment of night anxiety in children]" (in ru). Pediatriia 47 (8): 76–7. August 1968. PMID 5730033.