Chemistry:T-1152
From HandWiki
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Other names
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3D model (JSmol)
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PubChem CID
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CompTox Dashboard (EPA)
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| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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270 μg/kg (subcutaneous, mice)[1] 115 μg/kg (intravenous, mice)[1] 260 μg/kg (subcutaneous, rabbits)[1] |
LDLo (lowest published)
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2.5 mg/kg (oral, mice)[2] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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T-1152 is a quaternary carbamate anticholinesterase. It is synthesized by reaction of m-dimethylaminophenol with methyl isocyanate, followed by quaternization with methyl iodide.[3] Since T-1152 is toxic by ingestion, it was patented as a rodenticide in 1932.[2]
The chloride and methylsulfate salt of T-1152 is T-1690 (TL-1226) and AR-13, respectively.[1]
See also
References
- ↑ 1.0 1.1 1.2 1.3 Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. https://ntrl.ntis.gov/NTRL/dashboard/searchResults/titleDetail/PB158508.xhtml.
- ↑ 2.0 2.1 "Product for destroying animals". https://patents.google.com/patent/US1858177A.
- ↑ Stedman, Edgar (1 January 1926). "Studies on the Relationship between Chemical Constitution and Physiological Action". Biochemical Journal 20 (4): 719–734. doi:10.1042/bj0200719. PMID 16743713.
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