Chemistry:SKF-89,145

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Short description: Chemical compound
SKF-89,145
SKF-89,145 Structure.svg
Identifiers
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC14H15NO2S
Molar mass261.34 g·mol−1
3D model (JSmol)
  (verify)

SKF-89,145 is a drug which acts as a dopamine agonist selective for the D1 subtype. The N-desmethyl derivative SKF-89,626 is also a selective D1 agonist with similar potency and selectivity to SKF 89,145.[1]

References

  1. "New substituted 1-phenyl-3-benzazepine analogues of SK&F 38393 and N-methyl-thienopyridine analogues of dihydroxynomifensine with selective affinity for the D-1 dopamine receptor in human post-mortem brain". Neuropharmacology 26 (12): 1807–10. December 1987. doi:10.1016/0028-3908(87)90139-0. PMID 3501846.